Every breed has its specific health issues and the Lagotto Romagnolo is no exception. It is essential that animals with health problems are not used for breeding. The following hereditary problems (rarely) occur in the breed:
- HD (Hipdysplasia)
- PRA (Progressive Retina Atrophy)
- JE (Juvenile Epilepsy)
Dogs which are used for breeding, by breeders associated with the LRCN, are being tested for these anomalies on beforehand by means of X-Ray (HD), eyes examination (PRA/Cataract) and a DNA test (JE).